Crohn’s Disease (CD) is type of inflammatory bowel disease (IBD) which has been linked to the gut microbiome. FMT has been used in the treatment of CD by research scientists and doctors in clinical practice. Some studies have utilized FMT as a treatment for Crohn’s Disease.
Article Abstract 1:
Faecal Microbiota Transplantation for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.
J Crohns Colitis. 2017 May 9. doi: 10.1093/ecco-jcc/jjx063. [Epub ahead of print]
Faecal microbiota transplantation (FMT) has been investigated as a potential treatment for inflammatory bowel disease (IBD). We thus performed a systematic review and meta-analysis assessing the effectiveness and safety of FMT in IBD. A systematic review was conducted until Jan 2017. Studies were excluded if patients had co-infection or data was pooled across disease subtypes (ulcerative colitis (UC), Crohn’s disease (CD), pouchitis). Clinical remission was established as the primary outcome. Pooled effect sizes and 95% confidence intervals were obtained using the random effects model. 53 studies were included (41 in UC, 11 in CD, 4 in pouchitis). Overall, 36% (201/555) of UC, 50.5% (42/83) of CD and 21.5% (5/23) of pouchitis patients achieved clinical remission.