{"id":1602,"date":"2018-04-02T22:27:00","date_gmt":"2018-04-02T14:27:00","guid":{"rendered":"http:\/\/asiabiobank.com\/?page_id=1602"},"modified":"2018-04-18T19:23:29","modified_gmt":"2018-04-18T11:23:29","slug":"ibd-crohns-disease","status":"publish","type":"page","link":"http:\/\/asiabiobank.com\/zh-hant\/for-patients\/gi-conditions\/ibd-crohns-disease\/","title":{"rendered":"\u514b\u7f85\u6069\u6c0f\u75c5"},"content":{"rendered":"<h2>\u4ec0\u9ebc\u662f\u514b\u7f85\u6069\u6c0f\u75c5\uff1f<\/h2>\n<p>\u514b\u7f85\u6069\u6c0f\u75c5\u662f\u4e00\u7a2e\u6162\u6027\uff0c\u8907\u767c\u6027\u8178\u9053\u708e\u3002\u514b\u7f85\u6069\u6c0f\u75c5\u4e3b\u8981\u5728\u5169\u500b\u90e8\u4f4d\u75c5\u767c\uff0c\u5206\u5225\u662f\u8ff4\u8178\u548c\u7d50\u8178\u3002\u8ff4\u8178\u662f\u5c0f\u8178\u7684\u6700\u5f8c\u90e8\u5206\uff08\u8ff4\u8178\u708e\uff0c\u5340\u57df\u6027\u8178\u708e\uff09\uff1b\u7d50\u8178\uff08\u514b\u7f85\u6069\u6c0f\u7d50\u8178\u708e\uff09\u3002\u75c5\u60c5\u521d\u671f\u51fa\u73fe\u4e00\u7aa9\u7aa9\u5de2\u72c0\u5fae\u7d30\u7684\u767c\u708e\u75c7\u72c0\uff0c\u767c\u708e\u60c5\u6cc1\u6703\u6301\u7e8c\u4e26\u4e14\u64f4\u5927\u7bc4\u570d\u3002\u8178\u9053\u5167\u9ecf\u819c\u6703\u5c0e\u81f4\u6f70\u760d\u800c\u4ee4\u8178\u58c1\u8b8a\u539a\u3002\u6700\u7d42\uff0c\u6703\u56e0\u8178\u6703\u8b8a\u7a84\u6216\u963b\u585e\uff0c\u800c\u9700\u8981\u624b\u8853\u3002<\/p>\n<h4><span style=\"color: #000000; font-size: 17px;\"><strong>\u600e\u9ebc\u8a3a\u65b7\uff1f<\/strong><\/span><\/h4>\n<p><span style=\"color: #000000; font-size: 17px;\">\u75c5\u4eba\u7684\u75c5\u6b77\u548c\u8eab\u9ad4\u6aa2\u67e5\u5c0d\u65b7\u75c7\u5f88\u6709\u5e6b\u52a9\u3002\u8840\u6db2\u548c\u7cde\u4fbf\u5109\u9a57\u66f4\u80fd\u6e96\u78ba\u5730\u65b7\u75c7\u3002\u70ba\u5c0f\u8178\u548c\u7d50\u8178\u7167X\u5149\u4e5f\u6709\u52a9\u65b7\u75c7 \uff08\u5305\u62ec\u4e0a\u6d88\u5316\u9053\u4e26\u8207\u704c\u8178\u5291\u914d\u5408\u4f7f\u7528\uff09\u3002\u6b64\u5916\uff0c\u6709\u9700\u8981\u6642\uff0c\u6703\u4f7f\u7528\u4e59\u72c0\u7d50\u8178\u93e1\u6aa2\u67e5\u76f4\u8178\u548c\u4e0b\u6d88\u5316\u9053\u7684\u9ecf\u819c\u3002\u7d50\u8178\u93e1\u6aa2\u67e5\uff0c\u66f4\u80fd\u5fb9\u5e95\u5730\u6aa2\u67e5\u4e00\u6574\u689d\u7d50\u8178\uff0c \u662f\u6700\u6709\u6548\u7684\u8a3a\u65b7\u8178\u9053\u75be\u75c5\u7684\u65b9\u6cd5\u3002<\/span><\/p>\n<h4><strong>\u70ba\u4ec0\u9ebc\u4eba\u985e\u83cc\u7fa4\u79fb\u690d\u7642\u6cd5\uff08HMT\uff09\u8207\u514b\u7f85\u6069\u75c5\u7684\u75c7\u72c0\u6709\u95dc\uff1f<\/strong><\/h4>\n<p>\u708e\u75c7\u6027\u8178\u75c5\uff08IBD\uff09\u60a3\u8005\u7684\u8178\u9053\u83cc\u7fa4\u6703\u6709\u4e00\u9023\u4e32\u7684\u8b8a\u5316\u3002\u7576\u8178\u9053\u83cc\u7fa4\u9054\u5230\u6700\u9ad8\u6c34\u5e73\uff0c\u9019\u6a23\u6703\u4f7f\u8178\u9053\u83cc\u7fa4\u591a\u6a23\u6027\u4e0b\u964d\uff0c\u8b8a\u6210\u5931\u8861\u72c0\u614b\uff08\u7a31\u70ba\u83cc\u7fa4\u5931\u8abfdysbiosis\uff09\u3002HMT\u5df2\u88ab\u7814\u7a76\u8a3c\u5be6\u53ef\u6291\u5236\u514b\u7f85\u6069\u75c5\u7684\u75c7\u72c0\u3002\u5728\u6700\u8fd1\u7684\u4e00\u9805\u7d71\u8a08\u5206\u6790\u4e2d\u986f\u793a\u51fa\uff0c82\u4f4d\u60a3\u8005\u4e2d\u670942 \u4f4d \uff0850.5%\uff09\u63a5\u53d7\u4eba\u985e\u83cc\u7fa4\u79fb\u690d\u7642\u6cd5\u4e4b\u5f8c\uff0c\u75c7\u72c0\u7372\u5f97\u81e8\u5e8a\u4e0a\u7684\u7de9\u548c\uff0c\u4e26\u6c92\u6709\u660e\u986f\u7684\u526f\u4f5c\u75281\u3002<\/p>\n<h4><strong>\u4ec0\u9ebc\u662f\u9999\u6e2fHMT\u8a08\u5283 ?<\/strong><\/h4>\n<p>\u4e9e\u6d32\u76ca\u83cc\u4e2d\u5fc3\u8207\u672c\u5730\u77e5\u540d\u80c3\u8178\u75c5\u5c08\u5bb6\u7dca\u5bc6\u5408\u4f5c\u3002\u6211\u5011\u7684HMT\u6cbb\u7642\u7a0b\u5e8f\u662f\u7531\u6211\u5011\u7684\u8178\u80c3\u79d1\u5c08\u5bb6\u9867\u554f\u7684\u5efa\u8b70\u53ca\u56e0\u500b\u4eba\u9700\u8981\u800c\u8a02\u7acb\u51fa\u4f86\u3002<br \/>\n\u8a72\u8a08\u5283\u662f\u901a\u904e\u6062\u5fa9\u8178\u9053\u5167\u5fae\u751f\u7269\u83cc\u7fa4\u7684\u5e73\u8861\uff0c\u4f86\u5e6b\u52a9\u60a8\u7de9\u89e3\u4e0d\u9069\u7684\u75c7\u72c0\uff0c\u7531\u6b64\u7372\u5f97\u9577\u671f\u76ca\u8655\u3002<\/p>\n<h4><strong>\u8a08\u5283\u6982\u8981:<\/strong><\/h4>\n<ul>\n<li>\u60a3\u8005\u6703\u5b89\u6392\u57282-3\u9031\u5167\u63a5\u53d7\u9023\u7e8c\u4e94\u5929HMT\u7642\u7a0b\uff0c\u6216\u662f\u5169\u6b21\u7684\u4e94\u5929HMT\u7642\u7a0b\uff08\u7e3d\u517110\u5929\uff09\u3002<\/li>\n<li>HMT\u53ef\u901a\u904e\u704c\u8178\uff0c\u53e3\u670d\u81a0\u56ca\u6216\u7d50\u8178\u93e1\uff08\u9700\u8981\u984d\u5916\u8cbb\u7528\uff09\u4e0b\u503c\u5165\u5230\u8178\u9053\u5167\u3002<\/li>\n<li>\u5728\u63a5\u53d7HMT\u6cbb\u7642\u4e4b\u524d\uff0c\u500b\u9ad4\u5c07\u7d93\u6b77\u7531\u6a19\u6e96\u7684\u8178\u9053\u6e96\u5099\u6216\u7d50\u8178\u6c34\u704c\u6d17\u7d44\u6210\u7684\u8178\u9053\u6e96\u5099\u3002<\/li>\n<\/ul>\n<h4><strong>\u75c5\u4eba\u9808\u77e5<\/strong><\/h4>\n<p>\u4eba\u985e\u83cc\u7fa4\u79fb\u690d\u7642\u6cd5\uff08HMT\uff09\u4e3b\u8981\u76ee\u7684\u662f\u91cd\u65b0\u5e73\u8861\u60a3\u8005\u8178\u9053\u4e2d\u7684\u5fae\u751f\u7269\u7fa4\uff0c\u9019\u53ef\u4ee5\u8212\u7de9\u60a3\u8005\u8178\u9053\u7684\u76f8\u95dc\u75c7\u72c0\u3002\u6f70\u760d\u6027\u7d50\u8178\u708e\u662f\u4e00\u7a2e\u91ab\u5b78\u75be\u75c5\uff0c\u6cbb\u7642\u5fc5\u9808\u8981\u5728\u91ab\u751f\u7684\u76e3\u7763\u4e0b\u9032\u884c\u3002\u5982\u6709\u4efb\u4f55\u6709\u95dc\u85e5\u7269\u4e0a\u6216\u8655\u65b9\u4e0a\u7684\u554f\u984c\u8acb\u8aee\u8a62\u4f60\u5bb6\u5ead\u91ab\u751f\u3002\u56e0\u6b64\uff0c\u60a3\u8005\u5728\u63a5\u53d7\u6cbb\u7642\u4e4b\u524d\uff0c\u5fc5\u9808\u8981\u7372\u5f97\u91ab\u751f\u7c3d\u767c\u7684\u8f49\u4ecb\u4fe1\u3002<\/p>\n<p>&nbsp;<\/p>\n<h4>Further diagnosis details<\/h4>\n<p>Your doctor may ask to have further blood tests to test if you are anaemic and whether your illness has caused the level of protein to fall. In general, the greater the degree of anaemia and the lower the protein level, the more severe the inflammation is likely to be. Doctors also use special blood tests called ESR and CRP to give a measure of the degree of inflammation. You may be asked to give small samples of your bowel motions, to measure levels of faecal calprotectin, which is a marker of inflammation and to be sure there are no signs of any bowel infection.<\/p>\n<h4>Further microbiota details<\/h4>\n<p>In CD patients gut microbiome shifts, often these shifts include fewer bacteria in the Bacteroides and Lachnospiraceae groups (phyla), but more in the Proteobacteria and Actinobacteria groups (phyla). In addition, a decrease in a butyrate-producing bacterium, which is important in intestinal health, has been observed in patients with IBD. Therefore, researches around the world are exploring the efficacy and safety of FMT for CD patients including those patients who are unresponsive to current conventional therapy, such as anti-inflammatory agents, steroids, immune-suppressives, and biological therapies2.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"text-decoration: underline;\"><strong>Article Abstract 1:<\/strong><\/span><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28486648\">Faecal Microbiota Transplantation for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.<br \/>\n<\/a>J Crohns Colitis. 2017 May 9. doi: 10.1093\/ecco-jcc\/jjx063. [Epub ahead of print]<\/p>\n<p>Faecal microbiota transplantation (FMT) has been investigated as a potential treatment for inflammatory bowel disease (IBD). We thus performed a systematic review and meta-analysis assessing the effectiveness and safety of FMT in IBD. A systematic review was conducted until Jan 2017. Studies were excluded if patients had co-infection or data was pooled across disease subtypes (ulcerative colitis (UC), Crohn&#8217;s disease (CD), pouchitis). Clinical remission was established as the primary outcome. Pooled effect sizes and 95% confidence intervals were obtained using the random effects model. \u00a053 studies were included (41 in UC, 11 in CD, 4 in pouchitis). Overall, 36% (201\/555) of UC,<span style=\"text-decoration: underline;\"><strong> 50.5% (42\/83) of CD<\/strong><\/span> and 21.5% (5\/23) of pouchitis patients achieved clinical remission.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4ec0\u9ebc\u662f\u514b\u7f85\u6069\u6c0f\u75c5\uff1f \u514b\u7f85\u6069\u6c0f\u75c5\u662f\u4e00\u7a2e\u6162\u6027\uff0c\u8907\u767c\u6027\u8178\u9053\u708e\u3002\u514b\u7f85\u6069\u6c0f\u75c5\u4e3b\u8981\u5728\u5169\u500b\u90e8\u4f4d\u75c5\u767c\uff0c\u5206\u5225\u662f\u8ff4\u8178\u548c\u7d50\u8178\u3002\u8ff4\u8178\u662f\u5c0f\u8178\u7684\u6700\u5f8c\u90e8\u5206\uff08\u8ff4\u8178\u708e\uff0c\u5340\u57df\u6027\u8178\u708e\uff09\uff1b\u7d50\u8178\uff08\u514b\u7f85\u6069\u6c0f\u7d50\u8178\u708e\uff09\u3002\u75c5\u60c5\u521d\u671f\u51fa\u73fe\u4e00\u7aa9\u7aa9\u5de2\u72c0\u5fae\u7d30\u7684\u767c\u708e\u75c7\u72c0\uff0c\u767c\u708e\u60c5\u6cc1\u6703\u6301\u7e8c\u4e26\u4e14\u64f4\u5927\u7bc4\u570d\u3002\u8178\u9053\u5167\u9ecf\u819c\u6703\u5c0e\u81f4\u6f70\u760d\u800c\u4ee4\u8178\u58c1\u8b8a\u539a\u3002\u6700\u7d42\uff0c\u6703\u56e0\u8178\u6703\u8b8a\u7a84\u6216\u963b\u585e\uff0c\u800c\u9700\u8981\u624b\u8853\u3002 \u600e\u9ebc\u8a3a\u65b7\uff1f \u75c5\u4eba\u7684\u75c5\u6b77\u548c\u8eab\u9ad4\u6aa2\u67e5\u5c0d\u65b7\u75c7\u5f88\u6709\u5e6b\u52a9\u3002\u8840\u6db2\u548c\u7cde\u4fbf\u5109\u9a57\u66f4\u80fd\u6e96\u78ba\u5730\u65b7\u75c7\u3002\u70ba\u5c0f\u8178\u548c\u7d50\u8178\u7167X\u5149\u4e5f\u6709\u52a9\u65b7\u75c7 \uff08\u5305\u62ec\u4e0a\u6d88\u5316\u9053\u4e26\u8207\u704c\u8178\u5291\u914d\u5408\u4f7f\u7528\uff09\u3002\u6b64\u5916\uff0c\u6709\u9700\u8981\u6642\uff0c\u6703\u4f7f\u7528\u4e59\u72c0\u7d50\u8178\u93e1\u6aa2\u67e5\u76f4\u8178\u548c\u4e0b\u6d88\u5316\u9053\u7684\u9ecf\u819c\u3002\u7d50\u8178\u93e1\u6aa2\u67e5\uff0c\u66f4\u80fd\u5fb9\u5e95\u5730\u6aa2\u67e5\u4e00\u6574\u689d\u7d50\u8178\uff0c \u662f\u6700\u6709\u6548\u7684\u8a3a\u65b7\u8178\u9053\u75be\u75c5\u7684\u65b9\u6cd5\u3002 \u70ba\u4ec0\u9ebc\u4eba\u985e\u83cc\u7fa4\u79fb\u690d\u7642\u6cd5\uff08HMT\uff09\u8207\u514b\u7f85\u6069\u75c5\u7684\u75c7\u72c0\u6709\u95dc\uff1f \u708e\u75c7\u6027\u8178\u75c5\uff08IBD\uff09\u60a3\u8005\u7684\u8178\u9053\u83cc\u7fa4\u6703\u6709\u4e00\u9023\u4e32\u7684\u8b8a\u5316\u3002\u7576\u8178\u9053\u83cc\u7fa4\u9054\u5230\u6700\u9ad8\u6c34\u5e73\uff0c\u9019\u6a23\u6703\u4f7f\u8178\u9053\u83cc\u7fa4\u591a\u6a23\u6027\u4e0b\u964d\uff0c\u8b8a\u6210\u5931\u8861\u72c0\u614b\uff08\u7a31\u70ba\u83cc\u7fa4\u5931\u8abfdysbiosis\uff09\u3002HMT\u5df2\u88ab\u7814\u7a76\u8a3c\u5be6\u53ef\u6291\u5236\u514b\u7f85\u6069\u75c5\u7684\u75c7\u72c0\u3002\u5728\u6700\u8fd1\u7684\u4e00\u9805\u7d71\u8a08\u5206\u6790\u4e2d\u986f\u793a\u51fa\uff0c82\u4f4d\u60a3\u8005\u4e2d\u670942 \u4f4d \uff0850.5%\uff09\u63a5\u53d7\u4eba\u985e\u83cc\u7fa4\u79fb\u690d\u7642\u6cd5\u4e4b\u5f8c\uff0c\u75c7\u72c0\u7372\u5f97\u81e8\u5e8a\u4e0a\u7684\u7de9\u548c\uff0c\u4e26\u6c92\u6709\u660e\u986f\u7684\u526f\u4f5c\u75281\u3002 \u4ec0\u9ebc\u662f\u9999\u6e2fHMT\u8a08\u5283 ? \u4e9e\u6d32\u76ca\u83cc\u4e2d\u5fc3\u8207\u672c\u5730\u77e5\u540d\u80c3\u8178\u75c5\u5c08\u5bb6\u7dca\u5bc6\u5408\u4f5c\u3002\u6211\u5011\u7684HMT\u6cbb\u7642\u7a0b\u5e8f\u662f\u7531\u6211\u5011\u7684\u8178\u80c3\u79d1\u5c08\u5bb6\u9867\u554f\u7684\u5efa\u8b70\u53ca\u56e0\u500b\u4eba\u9700\u8981\u800c\u8a02\u7acb\u51fa\u4f86\u3002 \u8a72\u8a08\u5283\u662f\u901a\u904e\u6062\u5fa9\u8178\u9053\u5167\u5fae\u751f\u7269\u83cc\u7fa4\u7684\u5e73\u8861\uff0c\u4f86\u5e6b\u52a9\u60a8\u7de9\u89e3\u4e0d\u9069\u7684\u75c7\u72c0\uff0c\u7531\u6b64\u7372\u5f97\u9577\u671f\u76ca\u8655\u3002 \u8a08\u5283\u6982\u8981: \u60a3\u8005\u6703\u5b89\u6392\u57282-3\u9031\u5167\u63a5\u53d7\u9023\u7e8c\u4e94\u5929HMT\u7642\u7a0b\uff0c\u6216\u662f\u5169\u6b21\u7684\u4e94\u5929HMT\u7642\u7a0b\uff08\u7e3d\u517110\u5929\uff09\u3002 HMT\u53ef\u901a\u904e\u704c\u8178\uff0c\u53e3\u670d\u81a0\u56ca\u6216\u7d50\u8178\u93e1\uff08\u9700\u8981\u984d\u5916\u8cbb\u7528\uff09\u4e0b\u503c\u5165\u5230\u8178\u9053\u5167\u3002 \u5728\u63a5\u53d7HMT\u6cbb\u7642\u4e4b\u524d\uff0c\u500b\u9ad4\u5c07\u7d93\u6b77\u7531\u6a19\u6e96\u7684\u8178\u9053\u6e96\u5099\u6216\u7d50\u8178\u6c34\u704c\u6d17\u7d44\u6210\u7684\u8178\u9053\u6e96\u5099\u3002 \u75c5\u4eba\u9808\u77e5 \u4eba\u985e\u83cc\u7fa4\u79fb\u690d\u7642\u6cd5\uff08HMT\uff09\u4e3b\u8981\u76ee\u7684\u662f\u91cd\u65b0\u5e73\u8861\u60a3\u8005\u8178\u9053\u4e2d\u7684\u5fae\u751f\u7269\u7fa4\uff0c\u9019\u53ef\u4ee5\u8212\u7de9\u60a3\u8005\u8178\u9053\u7684\u76f8\u95dc\u75c7\u72c0\u3002\u6f70\u760d\u6027\u7d50\u8178\u708e\u662f\u4e00\u7a2e\u91ab\u5b78\u75be\u75c5\uff0c\u6cbb\u7642\u5fc5\u9808\u8981\u5728\u91ab\u751f\u7684\u76e3\u7763\u4e0b\u9032\u884c\u3002\u5982\u6709\u4efb\u4f55\u6709\u95dc\u85e5\u7269\u4e0a\u6216\u8655\u65b9\u4e0a\u7684\u554f\u984c\u8acb\u8aee\u8a62\u4f60\u5bb6\u5ead\u91ab\u751f\u3002\u56e0\u6b64\uff0c\u60a3\u8005\u5728\u63a5\u53d7\u6cbb\u7642\u4e4b\u524d\uff0c\u5fc5\u9808\u8981\u7372\u5f97\u91ab\u751f\u7c3d\u767c\u7684\u8f49\u4ecb\u4fe1\u3002 &nbsp; Further diagnosis details Your doctor may ask to have further blood tests to test if you are anaemic and whether your illness has caused the level of protein to fall. In general, the greater [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":1544,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"acf":[],"_links":{"self":[{"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/pages\/1602"}],"collection":[{"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=1602"}],"version-history":[{"count":5,"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/pages\/1602\/revisions"}],"predecessor-version":[{"id":1698,"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/pages\/1602\/revisions\/1698"}],"up":[{"embeddable":true,"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/pages\/1544"}],"wp:attachment":[{"href":"http:\/\/asiabiobank.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=1602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}